Glutathione hydrolase 7 (GGT7)
Homo sapiens — UniProt Q9UJ14
Data last refreshed: (UniProt release unknown)
Key facts
Glutathione hydrolase 7 (GGT7) is a protein from Homo sapiens identified by UniProt accession Q9UJ14, 662 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q9UJ14; gene symbol GGT7.
- Organism: Homo sapiens.
- Length: 662 amino acids.
- Top disease associations (Open Targets): age at menarche, creatinine measurement and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glutathione hydrolase 7 |
|---|---|
| UniProt accession | Q9UJ14 |
| Gene | GGT7 |
| Organism | Homo sapiens |
| Length | 662 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- age at menarche · score 0.28
- creatinine measurement · score 0.23
- glomerular filtration rate · score 0.19
- uric acid measurement · score 0.17
- urate measurement · score 0.13
- testosterone measurement · score 0.11
- body mass index · score 0.09
- angina pectoris · score 0.08
- lean body mass · score 0.08
- mean reticulocyte volume · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJ14-F1 | alphafold | PREDICTED | 85.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJ14.
Amino-acid sequence (662 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GGT7?
The strongest Open Targets associations for GGT7 are age at menarche, creatinine measurement, glomerular filtration rate, uric acid measurement and urate measurement.
How long is the GGT7 protein?
The Homo sapiens GGT7 protein (UniProt Q9UJ14) is 662 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJ14 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJ14 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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