Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2)
Homo sapiens — UniProt Q9UJ37
Data last refreshed: (UniProt release unknown)
Key facts
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (ST6GALNAC2) is a protein from Homo sapiens identified by UniProt accession Q9UJ37, 374 residues long. MolForge cross-references it against 0 known binders and 100 disease associations.
- UniProt accession: Q9UJ37; gene symbol ST6GALNAC2.
- Organism: Homo sapiens.
- Length: 374 amino acids.
- Top disease associations (Open Targets): COVID-19, severe acute respiratory syndrome and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
|---|---|
| UniProt accession | Q9UJ37 |
| Gene | ST6GALNAC2 |
| Organism | Homo sapiens |
| Length | 374 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (100)
Diseases linked to this target (Open Targets).
- COVID-19 · score 0.46
- severe acute respiratory syndrome · score 0.37
- neurodegenerative disease · score 0.26
- head and neck squamous cell carcinoma · score 0.12
- endometrial cancer · score 0.10
- breast adenocarcinoma · score 0.10
- gastric adenocarcinoma · score 0.10
- total cholesterol measurement · score 0.09
- neutrophil count · score 0.06
- isolated agammaglobulinemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJ37-F1 | alphafold | PREDICTED | 85.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJ37.
Amino-acid sequence (374 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ST6GALNAC2?
The strongest Open Targets associations for ST6GALNAC2 are COVID-19, severe acute respiratory syndrome, neurodegenerative disease, head and neck squamous cell carcinoma and endometrial cancer.
How long is the ST6GALNAC2 protein?
The Homo sapiens ST6GALNAC2 protein (UniProt Q9UJ37) is 374 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJ37 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJ37 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.