Probable G-protein coupled receptor 160 (GPR160)
Homo sapiens — UniProt Q9UJ42
Data last refreshed: (UniProt release unknown)
Key facts
Probable G-protein coupled receptor 160 (GPR160) is a protein from Homo sapiens identified by UniProt accession Q9UJ42, 338 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q9UJ42; gene symbol GPR160.
- Organism: Homo sapiens.
- Length: 338 amino acids.
- Top disease associations (Open Targets): Testicular Germ Cell Tumor, sclerosing cholangitis and psoriasis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable G-protein coupled receptor 160 |
|---|---|
| UniProt accession | Q9UJ42 |
| Gene | GPR160 |
| Organism | Homo sapiens |
| Length | 338 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- Testicular Germ Cell Tumor · score 0.23
- sclerosing cholangitis · score 0.16
- psoriasis · score 0.11
- lean body mass · score 0.11
- diastolic blood pressure · score 0.09
- appendicular lean mass · score 0.09
- fat body mass · score 0.09
- systolic blood pressure · score 0.09
- body weight · score 0.08
- body height · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJ42-F1 | alphafold | PREDICTED | 76.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJ42.
Amino-acid sequence (338 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GPR160?
The strongest Open Targets associations for GPR160 are Testicular Germ Cell Tumor, sclerosing cholangitis, psoriasis, lean body mass and diastolic blood pressure.
How long is the GPR160 protein?
The Homo sapiens GPR160 protein (UniProt Q9UJ42) is 338 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJ42 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJ42 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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