Mitochondrial peptide methionine sulfoxide reductase (MSRA)
Homo sapiens — UniProt Q9UJ68
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial peptide methionine sulfoxide reductase (MSRA) is a protein from Homo sapiens identified by UniProt accession Q9UJ68, 235 residues long. MolForge cross-references it against 0 known binders and 190 disease associations.
- UniProt accession: Q9UJ68; gene symbol MSRA.
- Organism: Homo sapiens.
- Length: 235 amino acids.
- Top disease associations (Open Targets): alcohol drinking, schizophrenia and type 2 diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial peptide methionine sulfoxide reductase |
|---|---|
| UniProt accession | Q9UJ68 |
| Gene | MSRA |
| Organism | Homo sapiens |
| Length | 235 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (190)
Diseases linked to this target (Open Targets).
- alcohol drinking · score 0.43
- schizophrenia · score 0.42
- type 2 diabetes mellitus · score 0.41
- diastolic blood pressure · score 0.39
- neuroticism measurement · score 0.38
- alcohol consumption measurement · score 0.38
- mathematical ability · score 0.37
- systolic blood pressure · score 0.37
- Barrett's esophagus · score 0.37
- neuroimaging measurement · score 0.36
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJ68-F1 | alphafold | PREDICTED | 88.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJ68.
Amino-acid sequence (235 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MSRA?
The strongest Open Targets associations for MSRA are alcohol drinking, schizophrenia, type 2 diabetes mellitus, diastolic blood pressure and neuroticism measurement.
How long is the MSRA protein?
The Homo sapiens MSRA protein (UniProt Q9UJ68) is 235 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJ68 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJ68 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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