N-acetyl-D-glucosamine kinase (NAGK)
Homo sapiens — UniProt Q9UJ70
Data last refreshed: (UniProt release unknown)
Key facts
N-acetyl-D-glucosamine kinase (NAGK) is a protein from Homo sapiens identified by UniProt accession Q9UJ70, 344 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q9UJ70; gene symbol NAGK.
- Organism: Homo sapiens.
- Length: 344 amino acids.
- Target class: Kinase.
- Top disease associations (Open Targets): eosinophil count, blood protein measurement and N-acetyl-D-glucosamine kinase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | N-acetyl-D-glucosamine kinase |
|---|---|
| UniProt accession | Q9UJ70 |
| Gene | NAGK |
| Organism | Homo sapiens |
| Length | 344 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Kinase (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.38
- blood protein measurement · score 0.37
- N-acetyl-D-glucosamine kinase measurement · score 0.25
- eosinophil percentage of leukocytes · score 0.24
- gut microbiome measurement · score 0.20
- neurodegenerative disease · score 0.20
- neoplasm · score 0.08
- MODY · score 0.06
- emotional symptom measurement · score 0.06
- diabetes mellitus, permanent neonatal 4 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJ70-F1 | alphafold | PREDICTED | 94.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJ70.
Amino-acid sequence (344 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NAGK?
The strongest Open Targets associations for NAGK are eosinophil count, blood protein measurement, N-acetyl-D-glucosamine kinase measurement, eosinophil percentage of leukocytes and gut microbiome measurement.
How long is the NAGK protein?
The Homo sapiens NAGK protein (UniProt Q9UJ70) is 344 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJ70 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJ70 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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