C-type lectin domain family 4 member K (CD207)
Homo sapiens — UniProt Q9UJ71
Data last refreshed: (UniProt release unknown)
Key facts
C-type lectin domain family 4 member K (CD207) is a protein from Homo sapiens identified by UniProt accession Q9UJ71, 328 residues long. MolForge cross-references it against 0 known binders and 234 disease associations.
- UniProt accession: Q9UJ71; gene symbol CD207.
- Organism: Homo sapiens.
- Length: 328 amino acids.
- Top disease associations (Open Targets): Birbeck granule deficiency, seasonal allergic rhinitis and atopic eczema.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-type lectin domain family 4 member K |
|---|---|
| UniProt accession | Q9UJ71 |
| Gene | CD207 |
| Organism | Homo sapiens |
| Length | 328 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (234)
Diseases linked to this target (Open Targets).
- Birbeck granule deficiency · score 0.41
- seasonal allergic rhinitis · score 0.36
- atopic eczema · score 0.32
- neurodegenerative disease · score 0.17
- gut microbiome measurement · score 0.10
- cancer · score 0.07
- chromosomal aberration frequency · score 0.06
- chronic obstructive pulmonary disease · score 0.06
- neutropenia-monocytopenia-deafness syndrome · score 0.06
- melanoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJ71-F1 | alphafold | PREDICTED | 86.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJ71.
Amino-acid sequence (328 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CD207?
The strongest Open Targets associations for CD207 are Birbeck granule deficiency, seasonal allergic rhinitis, atopic eczema, neurodegenerative disease and gut microbiome measurement.
How long is the CD207 protein?
The Homo sapiens CD207 protein (UniProt Q9UJ71) is 328 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJ71 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJ71 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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