Voltage-gated potassium channel regulatory subunit KCNG2 (KCNG2)
Homo sapiens — UniProt Q9UJ96
Data last refreshed: (UniProt release unknown)
Key facts
Voltage-gated potassium channel regulatory subunit KCNG2 (KCNG2) is a protein from Homo sapiens identified by UniProt accession Q9UJ96, 466 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.
- UniProt accession: Q9UJ96; gene symbol KCNG2.
- Organism: Homo sapiens.
- Length: 466 amino acids.
- Top disease associations (Open Targets): multiple sclerosis, Myasthenia gravis and schizophrenia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Voltage-gated potassium channel regulatory subunit KCNG2 |
|---|---|
| UniProt accession | Q9UJ96 |
| Gene | KCNG2 |
| Organism | Homo sapiens |
| Length | 466 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- multiple sclerosis · score 0.59
- Myasthenia gravis · score 0.57
- schizophrenia · score 0.47
- Muscle weakness · score 0.46
- small cell carcinoma · score 0.46
- secondary progressive multiple sclerosis · score 0.43
- self reported educational attainment · score 0.42
- age at first sexual intercourse measurement · score 0.39
- smoking status measurement · score 0.38
- leukocyte count · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJ96-F1 | alphafold | PREDICTED | 79.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJ96.
Amino-acid sequence (466 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KCNG2?
The strongest Open Targets associations for KCNG2 are multiple sclerosis, Myasthenia gravis, schizophrenia, Muscle weakness and small cell carcinoma.
How long is the KCNG2 protein?
The Homo sapiens KCNG2 protein (UniProt Q9UJ96) is 466 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJ96 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJ96 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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