Motile sperm domain-containing protein 1 (MOSPD1)
Homo sapiens — UniProt Q9UJG1
Data last refreshed: (UniProt release unknown)
Key facts
Motile sperm domain-containing protein 1 (MOSPD1) is a protein from Homo sapiens identified by UniProt accession Q9UJG1, 213 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q9UJG1; gene symbol MOSPD1.
- Organism: Homo sapiens.
- Length: 213 amino acids.
- Top disease associations (Open Targets): Blackfan-Diamond anemia, hereditary persistence of fetal hemoglobin-sickle cell disease syndrome and Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Motile sperm domain-containing protein 1 |
|---|---|
| UniProt accession | Q9UJG1 |
| Gene | MOSPD1 |
| Organism | Homo sapiens |
| Length | 213 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- Blackfan-Diamond anemia · score 0.08
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.08
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.07
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.07
- delta-beta-thalassemia · score 0.06
- hemoglobin D disease · score 0.06
- hemoglobin E-beta-thalassemia syndrome · score 0.06
- Beta-thalassemia · score 0.05
- Alpha-thalassemia · score 0.05
- hemolytic anemia due to adenylate kinase deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJG1-F1 | alphafold | PREDICTED | 78.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJG1.
Amino-acid sequence (213 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MOSPD1?
The strongest Open Targets associations for MOSPD1 are Blackfan-Diamond anemia, hereditary persistence of fetal hemoglobin-sickle cell disease syndrome, Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16, alpha thalassemia-intellectual disability syndrome type 1 and delta-beta-thalassemia.
How long is the MOSPD1 protein?
The Homo sapiens MOSPD1 protein (UniProt Q9UJG1) is 213 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJG1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJG1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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