RNA pseudouridylate synthase domain-containing protein 1 (RPUSD1)
Homo sapiens — UniProt Q9UJJ7
Data last refreshed: (UniProt release unknown)
Key facts
RNA pseudouridylate synthase domain-containing protein 1 (RPUSD1) is a protein from Homo sapiens identified by UniProt accession Q9UJJ7, 312 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9UJJ7; gene symbol RPUSD1.
- Organism: Homo sapiens.
- Length: 312 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, prostate carcinoma and prostate cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RNA pseudouridylate synthase domain-containing protein 1 |
|---|---|
| UniProt accession | Q9UJJ7 |
| Gene | RPUSD1 |
| Organism | Homo sapiens |
| Length | 312 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- mean corpuscular volume · score 0.11
- mean corpuscular hemoglobin concentration · score 0.06
- mean corpuscular hemoglobin · score 0.04
- mean reticulocyte volume · score 0.04
- appendicular lean mass · score 0.04
- body height · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJJ7-F1 | alphafold | PREDICTED | 86.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJJ7.
Amino-acid sequence (312 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RPUSD1?
The strongest Open Targets associations for RPUSD1 are neurodegenerative disease, prostate carcinoma, prostate cancer, Familial prostate cancer and mean corpuscular volume.
How long is the RPUSD1 protein?
The Homo sapiens RPUSD1 protein (UniProt Q9UJJ7) is 312 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJJ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJJ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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