18S rRNA aminocarboxypropyltransferase (TSR3)
Homo sapiens — UniProt Q9UJK0
Data last refreshed: (UniProt release unknown)
Key facts
18S rRNA aminocarboxypropyltransferase (TSR3) is a protein from Homo sapiens identified by UniProt accession Q9UJK0, 312 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q9UJK0; gene symbol TSR3.
- Organism: Homo sapiens.
- Length: 312 amino acids.
- Top disease associations (Open Targets): GNPTG-mucolipidosis, genetic disorder and YKL40 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | 18S rRNA aminocarboxypropyltransferase |
|---|---|
| UniProt accession | Q9UJK0 |
| Gene | TSR3 |
| Organism | Homo sapiens |
| Length | 312 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- GNPTG-mucolipidosis · score 0.16
- genetic disorder · score 0.12
- YKL40 measurement · score 0.04
- inflammatory biomarker measurement · score 0.04
- body height · score 0.03
- reticulocyte count · score 0.02
- glioblastoma multiforme · score 0.01
- atopic asthma · score 0.01
- colon carcinoma · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJK0-F1 | alphafold | PREDICTED | 74.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJK0.
Amino-acid sequence (312 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSR3?
The strongest Open Targets associations for TSR3 are GNPTG-mucolipidosis, genetic disorder, YKL40 measurement, inflammatory biomarker measurement and body height.
How long is the TSR3 protein?
The Homo sapiens TSR3 protein (UniProt Q9UJK0) is 312 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJK0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJK0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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