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Zinc finger protein 391 (ZNF391)

Homo sapiens — UniProt Q9UJN7

Gene: ZNF391Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 391 (ZNF391) is a protein from Homo sapiens identified by UniProt accession Q9UJN7, 358 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.

  • UniProt accession: Q9UJN7; gene symbol ZNF391.
  • Organism: Homo sapiens.
  • Length: 358 amino acids.
  • Top disease associations (Open Targets): schizophrenia, bipolar disorder and monocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 391
UniProt accessionQ9UJN7
GeneZNF391
OrganismHomo sapiens
Length358 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (80)

Diseases linked to this target (Open Targets).

  • schizophrenia · score 0.36
  • bipolar disorder · score 0.33
  • monocyte count · score 0.30
  • neutrophil count · score 0.30
  • alkaline phosphatase measurement · score 0.28
  • mean platelet volume · score 0.26
  • neuroticism measurement · score 0.24
  • body mass index · score 0.23
  • body height · score 0.22
  • depressive symptom measurement · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UJN7-F1alphafoldPREDICTED76.32—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJN7.

Amino-acid sequence (358 residues)

MESLRGNTAQ GPTNEEDYKN EGQLSRQTKC PAQKKSSFEN TVVRKVSVTL KEIFTGEEGP ESSEFSLSPN LDAQQKIPKG HGSPISRKNS KDNSDLIKHQ RLFSQRKPCK CNECEKAFSY QSDLLVHSRI HGGEKPFECN KCGKSFSRST HLIEHQRTHT GEKPYECNEC GKAFSRSTHL SLHQRIHTGE KPYECSECGK AFSRSTNLSQ HQRTHTQERP YKCNECGKAF GDRSTIIQHQ RIHTGENPYE CSKCGKAFSW ISSLTEHQRT HTGENPYECS ECGKVFSRSS SLTEHQRIHS GEKPHECRVC GKGFSRSSSL IIHQRTHTGE KPYKCNDCGK AFCQSSTLIR HQHLHTKE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF391?

The strongest Open Targets associations for ZNF391 are schizophrenia, bipolar disorder, monocyte count, neutrophil count and alkaline phosphatase measurement.

How long is the ZNF391 protein?

The Homo sapiens ZNF391 protein (UniProt Q9UJN7) is 358 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UJN7
GeneZNF391
OrganismHomo sapiens
Length358
Binders0
Diseases80
View on UniProt