Lysosome-associated membrane glycoprotein 5 (LAMP5)
Homo sapiens — UniProt Q9UJQ1
Data last refreshed: (UniProt release unknown)
Key facts
Lysosome-associated membrane glycoprotein 5 (LAMP5) is a protein from Homo sapiens identified by UniProt accession Q9UJQ1, 280 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q9UJQ1; gene symbol LAMP5.
- Organism: Homo sapiens.
- Length: 280 amino acids.
- Top disease associations (Open Targets): neutrophil count, protein measurement and Miyoshi myopathy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lysosome-associated membrane glycoprotein 5 |
|---|---|
| UniProt accession | Q9UJQ1 |
| Gene | LAMP5 |
| Organism | Homo sapiens |
| Length | 280 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.11
- protein measurement · score 0.11
- Miyoshi myopathy · score 0.08
- MODY · score 0.06
- diabetes mellitus, permanent neonatal 4 · score 0.05
- diabetes mellitus, transient neonatal, 3 · score 0.05
- permanent neonatal diabetes mellitus 1 · score 0.04
- hyperproinsulinemia · score 0.04
- Glycogen storage disease due to hepatic glycogen synthase deficiency · score 0.04
- glycogen storage disorder due to hepatic glycogen synthase deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJQ1-F1 | alphafold | PREDICTED | 86.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJQ1.
Amino-acid sequence (280 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LAMP5?
The strongest Open Targets associations for LAMP5 are neutrophil count, protein measurement, Miyoshi myopathy, MODY and diabetes mellitus, permanent neonatal 4.
How long is the LAMP5 protein?
The Homo sapiens LAMP5 protein (UniProt Q9UJQ1) is 280 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJQ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJQ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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