Sal-like protein 4 (SALL4)
Homo sapiens — UniProt Q9UJQ4
Data last refreshed: (UniProt release unknown)
Key facts
Sal-like protein 4 (SALL4) is a protein from Homo sapiens identified by UniProt accession Q9UJQ4, 1053 residues long. MolForge cross-references it against 0 known binders and 504 disease associations.
- UniProt accession: Q9UJQ4; gene symbol SALL4.
- Organism: Homo sapiens.
- Length: 1053 amino acids.
- Top disease associations (Open Targets): Duane-radial ray syndrome, IVIC syndrome and Okihiro syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sal-like protein 4 |
|---|---|
| UniProt accession | Q9UJQ4 |
| Gene | SALL4 |
| Organism | Homo sapiens |
| Length | 1053 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (504)
Diseases linked to this target (Open Targets).
- Duane-radial ray syndrome · score 0.83
- IVIC syndrome · score 0.72
- Okihiro syndrome · score 0.60
- neurodegenerative disease · score 0.55
- cutaneous melanoma · score 0.41
- lung adenocarcinoma · score 0.40
- melanoma · score 0.39
- colorectal adenocarcinoma · score 0.38
- gastric adenocarcinoma · score 0.37
- Duane retraction syndrome · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJQ4-F1 | alphafold | PREDICTED | 51.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJQ4.
Amino-acid sequence (1053 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SALL4?
The strongest Open Targets associations for SALL4 are Duane-radial ray syndrome, IVIC syndrome, Okihiro syndrome, neurodegenerative disease and cutaneous melanoma.
How long is the SALL4 protein?
The Homo sapiens SALL4 protein (UniProt Q9UJQ4) is 1053 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJQ4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJQ4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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