Tubulin epsilon chain (TUBE1)
Homo sapiens — UniProt Q9UJT0
Data last refreshed: (UniProt release unknown)
Key facts
Tubulin epsilon chain (TUBE1) is a protein from Homo sapiens identified by UniProt accession Q9UJT0, 475 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.
- UniProt accession: Q9UJT0; gene symbol TUBE1.
- Organism: Homo sapiens.
- Length: 475 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, attention deficit hyperactivity disorder and Tourette syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubulin epsilon chain |
|---|---|
| UniProt accession | Q9UJT0 |
| Gene | TUBE1 |
| Organism | Homo sapiens |
| Length | 475 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (48)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- attention deficit hyperactivity disorder · score 0.07
- Tourette syndrome · score 0.05
- metabolite measurement · score 0.05
- autism · score 0.05
- attention deficit-hyperactivity disorder 8 · score 0.05
- schizophrenia 15 · score 0.05
- protein measurement · score 0.05
- Phelan-McDermid syndrome · score 0.04
- X-linked non-syndromic intellectual disability · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJT0-F1 | alphafold | PREDICTED | 88.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJT0.
Amino-acid sequence (475 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TUBE1?
The strongest Open Targets associations for TUBE1 are neurodegenerative disease, attention deficit hyperactivity disorder, Tourette syndrome, metabolite measurement and autism.
How long is the TUBE1 protein?
The Homo sapiens TUBE1 protein (UniProt Q9UJT0) is 475 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJT0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJT0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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