Drebrin-like protein (DBNL)
Homo sapiens — UniProt Q9UJU6
Data last refreshed: (UniProt release unknown)
Key facts
Drebrin-like protein (DBNL) is a protein from Homo sapiens identified by UniProt accession Q9UJU6, 430 residues long. MolForge cross-references it against 0 known binders and 208 disease associations.
- UniProt accession: Q9UJU6; gene symbol DBNL.
- Organism: Homo sapiens.
- Length: 430 amino acids.
- Top disease associations (Open Targets): glycogen storage disease due to phosphoglycerate mutase deficiency, rhabdomyolysis and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Drebrin-like protein |
|---|---|
| UniProt accession | Q9UJU6 |
| Gene | DBNL |
| Organism | Homo sapiens |
| Length | 430 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (208)
Diseases linked to this target (Open Targets).
- glycogen storage disease due to phosphoglycerate mutase deficiency · score 0.55
- rhabdomyolysis · score 0.26
- mean platelet volume · score 0.25
- breast adenocarcinoma · score 0.25
- sitting height measurement · score 0.23
- ovarian cancer · score 0.23
- genetic disorder · score 0.19
- reticulocyte measurement · score 0.18
- proline measurement · score 0.14
- head and neck squamous cell carcinoma · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJU6-F1 | alphafold | PREDICTED | 74.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJU6.
Amino-acid sequence (430 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DBNL?
The strongest Open Targets associations for DBNL are glycogen storage disease due to phosphoglycerate mutase deficiency, rhabdomyolysis, mean platelet volume, breast adenocarcinoma and sitting height measurement.
How long is the DBNL protein?
The Homo sapiens DBNL protein (UniProt Q9UJU6) is 430 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJU6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJU6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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