Purine-rich element-binding protein gamma (PURG)
Homo sapiens — UniProt Q9UJV8
Data last refreshed: (UniProt release unknown)
Key facts
Purine-rich element-binding protein gamma (PURG) is a protein from Homo sapiens identified by UniProt accession Q9UJV8, 347 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q9UJV8; gene symbol PURG.
- Organism: Homo sapiens.
- Length: 347 amino acids.
- Top disease associations (Open Targets): body mass index, body fat percentage and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Purine-rich element-binding protein gamma |
|---|---|
| UniProt accession | Q9UJV8 |
| Gene | PURG |
| Organism | Homo sapiens |
| Length | 347 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- body mass index · score 0.45
- body fat percentage · score 0.45
- mathematical ability · score 0.43
- type 2 diabetes mellitus · score 0.43
- self reported educational attainment · score 0.43
- fat body mass · score 0.41
- body weight · score 0.41
- lean body mass · score 0.41
- waist-hip ratio · score 0.38
- intelligence · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJV8-F1 | alphafold | PREDICTED | 71.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJV8.
Amino-acid sequence (347 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PURG?
The strongest Open Targets associations for PURG are body mass index, body fat percentage, mathematical ability, type 2 diabetes mellitus and self reported educational attainment.
How long is the PURG protein?
The Homo sapiens PURG protein (UniProt Q9UJV8) is 347 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJV8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJV8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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