Tubulointerstitial nephritis antigen (TINAG)
Homo sapiens — UniProt Q9UJW2
Data last refreshed: (UniProt release unknown)
Key facts
Tubulointerstitial nephritis antigen (TINAG) is a protein from Homo sapiens identified by UniProt accession Q9UJW2, 476 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q9UJW2; gene symbol TINAG.
- Organism: Homo sapiens.
- Length: 476 amino acids.
- Top disease associations (Open Targets): age-related hearing impairment, diet measurement and pulse pressure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubulointerstitial nephritis antigen |
|---|---|
| UniProt accession | Q9UJW2 |
| Gene | TINAG |
| Organism | Homo sapiens |
| Length | 476 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- age-related hearing impairment · score 0.20
- diet measurement · score 0.09
- pulse pressure measurement · score 0.08
- PHF-tau measurement · score 0.06
- Barrett's esophagus · score 0.06
- hepatocellular carcinoma · score 0.05
- lean body mass · score 0.05
- body mass index · score 0.04
- adolescent idiopathic scoliosis · score 0.04
- esophageal adenocarcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJW2-F1 | alphafold | PREDICTED | 83.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJW2.
Amino-acid sequence (476 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TINAG?
The strongest Open Targets associations for TINAG are age-related hearing impairment, diet measurement, pulse pressure measurement, PHF-tau measurement and Barrett's esophagus.
How long is the TINAG protein?
The Homo sapiens TINAG protein (UniProt Q9UJW2) is 476 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJW2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJW2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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