Zinc finger protein 229 (ZNF229)
Homo sapiens — UniProt Q9UJW7
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 229 (ZNF229) is a protein from Homo sapiens identified by UniProt accession Q9UJW7, 825 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q9UJW7; gene symbol ZNF229.
- Organism: Homo sapiens.
- Length: 825 amino acids.
- Top disease associations (Open Targets): apolipoprotein B measurement, low density lipoprotein cholesterol measurement and total cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 229 |
|---|---|
| UniProt accession | Q9UJW7 |
| Gene | ZNF229 |
| Organism | Homo sapiens |
| Length | 825 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- apolipoprotein B measurement · score 0.55
- low density lipoprotein cholesterol measurement · score 0.53
- total cholesterol measurement · score 0.46
- free cholesterol in small LDL measurement · score 0.37
- cholesteryl ester measurement · score 0.36
- phospholipids in small LDL measurement · score 0.35
- free cholesterol in LDL measurement · score 0.30
- free cholesterol in medium LDL measurement · score 0.29
- phospholipids:total lipids ratio · score 0.28
- free cholesterol in large LDL measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJW7-F1 | alphafold | PREDICTED | 62.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJW7.
Amino-acid sequence (825 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF229?
The strongest Open Targets associations for ZNF229 are apolipoprotein B measurement, low density lipoprotein cholesterol measurement, total cholesterol measurement, free cholesterol in small LDL measurement and cholesteryl ester measurement.
How long is the ZNF229 protein?
The Homo sapiens ZNF229 protein (UniProt Q9UJW7) is 825 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJW7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJW7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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