Zinc finger protein 180 (ZNF180)
Homo sapiens — UniProt Q9UJW8
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 180 (ZNF180) is a protein from Homo sapiens identified by UniProt accession Q9UJW8, 692 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q9UJW8; gene symbol ZNF180.
- Organism: Homo sapiens.
- Length: 692 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, melanoma and mucocutaneous lymph node syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 180 |
|---|---|
| UniProt accession | Q9UJW8 |
| Gene | ZNF180 |
| Organism | Homo sapiens |
| Length | 692 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- melanoma · score 0.03
- mucocutaneous lymph node syndrome · score 0.03
- neoplasm · score 0.01
- cancer · score 0.01
- Herpes simplex infection · score 0.00
- nonpapillary renal cell carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJW8-F1 | alphafold | PREDICTED | 61.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJW8.
Amino-acid sequence (692 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF180?
The strongest Open Targets associations for ZNF180 are neurodegenerative disease, melanoma, mucocutaneous lymph node syndrome, neoplasm and cancer.
How long is the ZNF180 protein?
The Homo sapiens ZNF180 protein (UniProt Q9UJW8) is 692 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJW8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJW8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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