Oxidative stress-induced growth inhibitor 1 (OSGIN1)
Homo sapiens — UniProt Q9UJX0
Data last refreshed: (UniProt release unknown)
Key facts
Oxidative stress-induced growth inhibitor 1 (OSGIN1) is a protein from Homo sapiens identified by UniProt accession Q9UJX0, 477 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q9UJX0; gene symbol OSGIN1.
- Organism: Homo sapiens.
- Length: 477 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, low density lipoprotein cholesterol measurement and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Oxidative stress-induced growth inhibitor 1 |
|---|---|
| UniProt accession | Q9UJX0 |
| Gene | OSGIN1 |
| Organism | Homo sapiens |
| Length | 477 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.50
- low density lipoprotein cholesterol measurement · score 0.45
- sex hormone-binding globulin measurement · score 0.40
- serum albumin measurement · score 0.40
- C-reactive protein measurement · score 0.40
- testosterone measurement · score 0.39
- total cholesterol measurement · score 0.39
- body height · score 0.37
- calcium measurement · score 0.36
- platelet count · score 0.36
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJX0-F1 | alphafold | PREDICTED | 88.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJX0.
Amino-acid sequence (477 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OSGIN1?
The strongest Open Targets associations for OSGIN1 are alkaline phosphatase measurement, low density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement, serum albumin measurement and C-reactive protein measurement.
How long is the OSGIN1 protein?
The Homo sapiens OSGIN1 protein (UniProt Q9UJX0) is 477 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJX0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJX0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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