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Cell division cycle protein 23 homolog (CDC23)

Homo sapiens — UniProt Q9UJX2

Gene: CDC23Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Cell division cycle protein 23 homolog (CDC23) is a protein from Homo sapiens identified by UniProt accession Q9UJX2, 597 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.

  • UniProt accession: Q9UJX2; gene symbol CDC23.
  • Organism: Homo sapiens.
  • Length: 597 amino acids.
  • Top disease associations (Open Targets): glioblastoma multiforme, endometrial cancer and lung adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCell division cycle protein 23 homolog
UniProt accessionQ9UJX2
GeneCDC23
OrganismHomo sapiens
Length597 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (69)

Diseases linked to this target (Open Targets).

  • glioblastoma multiforme · score 0.20
  • endometrial cancer · score 0.18
  • lung adenocarcinoma · score 0.18
  • clear cell renal carcinoma · score 0.18
  • esophageal cancer · score 0.13
  • lower respiratory tract disease · score 0.11
  • head and neck squamous cell carcinoma · score 0.10
  • QT interval · score 0.08
  • Female infertility due to fertilization defect · score 0.07
  • Griscelli syndrome type 3 · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UJX2-F1alphafoldPREDICTED84.89—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJX2.

Amino-acid sequence (597 residues)

MAASTSMVPV AVTAAVAPVL SINSDFSDLR EIKKQLLLIA GLTRERGLLH SSKWSAELAF SLPALPLAEL QPPPPITEED AQDMDAYTLA KAYFDVKEYD RAAHFLHGCN SKKAYFLYMY SRYLSGEKKK DDETVDSLGP LEKGQVKNEA LRELRVELSK KHQARELDGF GLYLYGVVLR KLDLVKEAID VFVEATHVLP LHWGAWLELC NLITDKEMLK FLSLPDTWMK EFFLAHIYTE LQLIEEALQK YQNLIDVGFS KSSYIVSQIA VAYHNIRDID KALSIFNELR KQDPYRIENM DTFSNLLYVR SMKSELSYLA HNLCEIDKYR VETCCVIGNY YSLRSQHEKA ALYFQRALKL NPRYLGAWTL MGHEYMEMKN TSAAIQAYRH AIEVNKRDYR AWYGLGQTYE ILKMPFYCLY YYRRAHQLRP NDSRMLVALG ECYEKLNQLV EAKKCYWRAY AVGDVEKMAL VKLAKLHEQL TESEQAAQCY IKYIQDIYSC GEIVEHLEES TAFRYLAQYY FKCKLWDEAS TCAQKCCAFN DTREEGKALL RQILQLRNQG ETPTTEVPAP FFLPASLSAN NTPTRRVSPL NLSSVTP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CDC23?

The strongest Open Targets associations for CDC23 are glioblastoma multiforme, endometrial cancer, lung adenocarcinoma, clear cell renal carcinoma and esophageal cancer.

How long is the CDC23 protein?

The Homo sapiens CDC23 protein (UniProt Q9UJX2) is 597 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UJX2
GeneCDC23
OrganismHomo sapiens
Length597
Binders0
Diseases69
View on UniProt