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Anaphase-promoting complex subunit 7 (ANAPC7)

Homo sapiens — UniProt Q9UJX3

Gene: ANAPC7Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Anaphase-promoting complex subunit 7 (ANAPC7) is a protein from Homo sapiens identified by UniProt accession Q9UJX3, 565 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

  • UniProt accession: Q9UJX3; gene symbol ANAPC7.
  • Organism: Homo sapiens.
  • Length: 565 amino acids.
  • Top disease associations (Open Targets): Ferguson-Bonni neurodevelopmental syndrome, low grade glioma and breast adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameAnaphase-promoting complex subunit 7
UniProt accessionQ9UJX3
GeneANAPC7
OrganismHomo sapiens
Length565 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (53)

Diseases linked to this target (Open Targets).

  • Ferguson-Bonni neurodevelopmental syndrome · score 0.47
  • low grade glioma · score 0.25
  • breast adenocarcinoma · score 0.25
  • neurodegenerative disease · score 0.23
  • lung adenocarcinoma · score 0.18
  • clear cell renal carcinoma · score 0.18
  • head and neck squamous cell carcinoma · score 0.10
  • body fat percentage · score 0.08
  • erythrocyte count · score 0.08
  • body mass index · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UJX3-F1alphafoldPREDICTED82.98—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJX3.

Amino-acid sequence (565 residues)

MNVIDHVRDM AAAGLHSNVR LLSSLLLTMS NNNPELFSPP QKYQLLVYHA DSLFHDKEYR NAVSKYTMAL QQKKALSKTS KVRPSTGNSA STPQSQCLPS EIEVKYKMAE CYTMLKQDKD AIAILDGIPS RQRTPKINMM LANLYKKAGQ ERPSVTSYKE VLRQCPLALD AILGLLSLSV KGAEVASMTM NVIQTVPNLD WLSVWIKAYA FVHTGDNSRA ISTICSLEKK SLLRDNVDLL GSLADLYFRA GDNKNSVLKF EQAQMLDPYL IKGMDVYGYL LAREGRLEDV ENLGCRLFNI SDQHAEPWVV SGCHSFYSKR YSRALYLGAK AIQLNSNSVQ ALLLKGAALR NMGRVQEAII HFREAIRLAP CRLDCYEGLI ECYLASNSIR EAMVMANNVY KTLGANAQTL TLLATVCLED PVTQEKAKTL LDKALTQRPD YIKAVVKKAE LLSREQKYED GIALLRNALA NQSDCVLHRI LGDFLVAVNE YQEAMDQYSI ALSLDPNDQK SLEGMQKMEK EESPTDATQE EDVDDMEGSG EEGDLEGSDS EAAQWADQEQ WFGMQ

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ANAPC7?

The strongest Open Targets associations for ANAPC7 are Ferguson-Bonni neurodevelopmental syndrome, low grade glioma, breast adenocarcinoma, neurodegenerative disease and lung adenocarcinoma.

How long is the ANAPC7 protein?

The Homo sapiens ANAPC7 protein (UniProt Q9UJX3) is 565 amino acids long.

Browse: Targets: A · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UJX3
GeneANAPC7
OrganismHomo sapiens
Length565
Binders0
Diseases53
View on UniProt