Anaphase-promoting complex subunit 5 (ANAPC5)
Homo sapiens — UniProt Q9UJX4
Data last refreshed: (UniProt release unknown)
Key facts
Anaphase-promoting complex subunit 5 (ANAPC5) is a protein from Homo sapiens identified by UniProt accession Q9UJX4, 755 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q9UJX4; gene symbol ANAPC5.
- Organism: Homo sapiens.
- Length: 755 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, breast adenocarcinoma and ovarian cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anaphase-promoting complex subunit 5 |
|---|---|
| UniProt accession | Q9UJX4 |
| Gene | ANAPC5 |
| Organism | Homo sapiens |
| Length | 755 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- breast adenocarcinoma · score 0.25
- ovarian cancer · score 0.23
- diastolic blood pressure · score 0.19
- clear cell renal carcinoma · score 0.18
- endometrial cancer · score 0.18
- lung adenocarcinoma · score 0.18
- body height · score 0.18
- lymphocyte percentage of leukocytes · score 0.18
- lymphocyte count · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJX4-F1 | alphafold | PREDICTED | 81.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJX4.
Amino-acid sequence (755 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANAPC5?
The strongest Open Targets associations for ANAPC5 are neurodegenerative disease, breast adenocarcinoma, ovarian cancer, diastolic blood pressure and clear cell renal carcinoma.
How long is the ANAPC5 protein?
The Homo sapiens ANAPC5 protein (UniProt Q9UJX4) is 755 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJX4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJX4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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