Anaphase-promoting complex subunit 2 (ANAPC2)
Homo sapiens — UniProt Q9UJX6
Data last refreshed: (UniProt release unknown)
Key facts
Anaphase-promoting complex subunit 2 (ANAPC2) is a protein from Homo sapiens identified by UniProt accession Q9UJX6, 822 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q9UJX6; gene symbol ANAPC2.
- Organism: Homo sapiens.
- Length: 822 amino acids.
- Top disease associations (Open Targets): low grade glioma, breast adenocarcinoma and ovarian cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anaphase-promoting complex subunit 2 |
|---|---|
| UniProt accession | Q9UJX6 |
| Gene | ANAPC2 |
| Organism | Homo sapiens |
| Length | 822 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- low grade glioma · score 0.25
- breast adenocarcinoma · score 0.25
- ovarian cancer · score 0.23
- neurodegenerative disease · score 0.22
- endometrial cancer · score 0.18
- lung adenocarcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- esophageal cancer · score 0.13
- eosinophil percentage of leukocytes · score 0.12
- sitting height measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJX6-F1 | alphafold | PREDICTED | 78.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJX6.
Amino-acid sequence (822 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANAPC2?
The strongest Open Targets associations for ANAPC2 are low grade glioma, breast adenocarcinoma, ovarian cancer, neurodegenerative disease and endometrial cancer.
How long is the ANAPC2 protein?
The Homo sapiens ANAPC2 protein (UniProt Q9UJX6) is 822 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJX6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJX6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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