ADP-ribosylation factor-binding protein GGA1 (GGA1)
Homo sapiens — UniProt Q9UJY5
Data last refreshed: (UniProt release unknown)
Key facts
ADP-ribosylation factor-binding protein GGA1 (GGA1) is a protein from Homo sapiens identified by UniProt accession Q9UJY5, 639 residues long. MolForge cross-references it against 0 known binders and 112 disease associations.
- UniProt accession: Q9UJY5; gene symbol GGA1.
- Organism: Homo sapiens.
- Length: 639 amino acids.
- Top disease associations (Open Targets): leukocyte count, myeloid white cell count and reticulocyte measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ADP-ribosylation factor-binding protein GGA1 |
|---|---|
| UniProt accession | Q9UJY5 |
| Gene | GGA1 |
| Organism | Homo sapiens |
| Length | 639 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (112)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.10
- myeloid white cell count · score 0.10
- reticulocyte measurement · score 0.09
- serum albumin measurement · score 0.09
- azoospermia · score 0.08
- partial chromosome Y deletion · score 0.06
- isolated congenital hypogonadotropic hypogonadism · score 0.06
- blood protein measurement · score 0.05
- spermatogenic failures 50 · score 0.05
- spermatogenic failure, X-linked, 2 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJY5-F1 | alphafold | PREDICTED | 73.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJY5.
Amino-acid sequence (639 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GGA1?
The strongest Open Targets associations for GGA1 are leukocyte count, myeloid white cell count, reticulocyte measurement, serum albumin measurement and azoospermia.
How long is the GGA1 protein?
The Homo sapiens GGA1 protein (UniProt Q9UJY5) is 639 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJY5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJY5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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