Zinc finger protein 223 (ZNF223)

About Zinc finger protein 223

Zinc finger protein 223 (ZNF223) is a protein from Homo sapiens identified by UniProt accession Q9UK11, 482 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Zinc finger protein 223
UniProt accession	Q9UK11
Gene	ZNF223
Organism	Homo sapiens
Length	482 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

protein measurement · score 0.03
Ataxia-telangiectasia · score 0.01
Lyme disease · score 0.00
ovarian carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UK11-F1	alphafold	PREDICTED	64.24	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UK11.

Amino-acid sequence (482 residues)

MTMSKEAVTF KDVAVVFTEE ELGLLDLAQR KLYRDVMLEN FRNLLSVGHQ PFHRDTFHFL REEKFWMMDI ATQREGNSGG KIQPEMKTFP EAGPHEGWSC QQIWEEIASD LTRPQDSTIK SSQFFEQGDA HSQVEEGLSI MHTGQKPSNC GKCKQSFSDM SIFDLPQQIR SAEKSHSCDE CGKSFCYISA LHIHQRVHLG EKLFKCDVCG KEFSQSLHLQ THQRVHTGEK PFKCEQCGRG FRCRSALTVH CKLHMGEKHY NCEACGRAFI HDFQLQKHQR IHTGEKPFKC EICSVSFRLR SSLNRHCVVH TGKKPNSTGE YGKGFIRRLD LCKHQTIHTG EKPYNCKECG KSFRRSSYLL IHQRVHTGEK PYKCDKCGKS YITKSGLDLH HRAHTGERPY NCDDCGKSFR QASSILNHKR LHCRKKPFKC EDCGKKLVYR SYRKDQQKNH SGENPSKCED CGKRYKRRLN LDIILSLFLN DT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards