Zinc finger protein 221 (ZNF221)
Homo sapiens — UniProt Q9UK13
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 221 (ZNF221) is a protein from Homo sapiens identified by UniProt accession Q9UK13, 617 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q9UK13; gene symbol ZNF221.
- Organism: Homo sapiens.
- Length: 617 amino acids.
- Top disease associations (Open Targets): protein measurement, YKL40 measurement and inflammatory biomarker measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 221 |
|---|---|
| UniProt accession | Q9UK13 |
| Gene | ZNF221 |
| Organism | Homo sapiens |
| Length | 617 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.07
- YKL40 measurement · score 0.06
- inflammatory biomarker measurement · score 0.06
- alkaline phosphatase measurement · score 0.02
- IGA glomerulonephritis · score 0.00
- idiopathic pulmonary arterial hypertension · score 0.00
- Lyme disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UK13-F1 | alphafold | PREDICTED | 70.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UK13.
Amino-acid sequence (617 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF221?
The strongest Open Targets associations for ZNF221 are protein measurement, YKL40 measurement, inflammatory biomarker measurement, alkaline phosphatase measurement and IGA glomerulonephritis.
How long is the ZNF221 protein?
The Homo sapiens ZNF221 protein (UniProt Q9UK13) is 617 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UK13 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UK13 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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