Calcipressin-3 (RCAN3)
Homo sapiens — UniProt Q9UKA8
Data last refreshed: (UniProt release unknown)
Key facts
Calcipressin-3 (RCAN3) is a protein from Homo sapiens identified by UniProt accession Q9UKA8, 241 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.
- UniProt accession: Q9UKA8; gene symbol RCAN3.
- Organism: Homo sapiens.
- Length: 241 amino acids.
- Top disease associations (Open Targets): severe acute respiratory syndrome, hair color and skin disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calcipressin-3 |
|---|---|
| UniProt accession | Q9UKA8 |
| Gene | RCAN3 |
| Organism | Homo sapiens |
| Length | 241 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- severe acute respiratory syndrome · score 0.37
- hair color · score 0.23
- skin disease · score 0.21
- hematologic disease · score 0.17
- peripheral arterial disease · score 0.07
- Romano-Ward syndrome · score 0.07
- familial atrial fibrillation · score 0.07
- Brugada syndrome · score 0.07
- Familial short QT syndrome · score 0.06
- Arrhythmogenic right ventricular dysplasia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKA8-F1 | alphafold | PREDICTED | 74.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKA8.
Amino-acid sequence (241 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RCAN3?
The strongest Open Targets associations for RCAN3 are severe acute respiratory syndrome, hair color, skin disease, hematologic disease and peripheral arterial disease.
How long is the RCAN3 protein?
The Homo sapiens RCAN3 protein (UniProt Q9UKA8) is 241 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKA8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKA8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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