Adherens junction-associated protein 1 (AJAP1)
Homo sapiens — UniProt Q9UKB5
Data last refreshed: (UniProt release unknown)
Key facts
Adherens junction-associated protein 1 (AJAP1) is a protein from Homo sapiens identified by UniProt accession Q9UKB5, 411 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q9UKB5; gene symbol AJAP1.
- Organism: Homo sapiens.
- Length: 411 amino acids.
- Top disease associations (Open Targets): smoking status measurement, systolic blood pressure and alcohol consumption measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adherens junction-associated protein 1 |
|---|---|
| UniProt accession | Q9UKB5 |
| Gene | AJAP1 |
| Organism | Homo sapiens |
| Length | 411 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- smoking status measurement · score 0.40
- systolic blood pressure · score 0.40
- alcohol consumption measurement · score 0.36
- adolescent idiopathic scoliosis · score 0.32
- chronotype measurement · score 0.31
- dental caries · score 0.25
- self reported educational attainment · score 0.24
- amyloid-beta measurement · score 0.21
- protein measurement · score 0.20
- PHF-tau measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKB5-F1 | alphafold | PREDICTED | 50.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKB5.
Amino-acid sequence (411 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AJAP1?
The strongest Open Targets associations for AJAP1 are smoking status measurement, systolic blood pressure, alcohol consumption measurement, adolescent idiopathic scoliosis and chronotype measurement.
How long is the AJAP1 protein?
The Homo sapiens AJAP1 protein (UniProt Q9UKB5) is 411 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKB5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKB5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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