Glucocorticoid modulatory element-binding protein 2 (GMEB2)
Homo sapiens — UniProt Q9UKD1
Data last refreshed: (UniProt release unknown)
Key facts
Glucocorticoid modulatory element-binding protein 2 (GMEB2) is a protein from Homo sapiens identified by UniProt accession Q9UKD1, 530 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9UKD1; gene symbol GMEB2.
- Organism: Homo sapiens.
- Length: 530 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, electrocardiography and prostate carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glucocorticoid modulatory element-binding protein 2 |
|---|---|
| UniProt accession | Q9UKD1 |
| Gene | GMEB2 |
| Organism | Homo sapiens |
| Length | 530 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- electrocardiography · score 0.18
- prostate carcinoma · score 0.14
- male reproductive organ cancer · score 0.13
- self reported educational attainment · score 0.13
- prostate cancer · score 0.11
- reticulocyte count · score 0.09
- eosinophil count · score 0.09
- neutrophil count · score 0.08
- cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKD1-F1 | alphafold | PREDICTED | 59.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKD1.
Amino-acid sequence (530 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GMEB2?
The strongest Open Targets associations for GMEB2 are neurodegenerative disease, electrocardiography, prostate carcinoma, male reproductive organ cancer and self reported educational attainment.
How long is the GMEB2 protein?
The Homo sapiens GMEB2 protein (UniProt Q9UKD1) is 530 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKD1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKD1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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