Disintegrin and metalloproteinase domain-containing protein 30 (ADAM30)
Homo sapiens — UniProt Q9UKF2
Data last refreshed: (UniProt release unknown)
Key facts
Disintegrin and metalloproteinase domain-containing protein 30 (ADAM30) is a protein from Homo sapiens identified by UniProt accession Q9UKF2, 790 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9UKF2; gene symbol ADAM30.
- Organism: Homo sapiens.
- Length: 790 amino acids.
- Top disease associations (Open Targets): Crohn's disease, lymphocyte count and cutaneous melanoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Disintegrin and metalloproteinase domain-containing protein 30 |
|---|---|
| UniProt accession | Q9UKF2 |
| Gene | ADAM30 |
| Organism | Homo sapiens |
| Length | 790 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- Crohn's disease · score 0.34
- lymphocyte count · score 0.30
- cutaneous melanoma · score 0.30
- type 2 diabetes mellitus · score 0.29
- diabetes mellitus · score 0.27
- serum gamma-glutamyl transferase measurement · score 0.26
- lung adenocarcinoma · score 0.25
- granulocyte count · score 0.24
- HbA1c measurement · score 0.24
- squamous cell lung carcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKF2-F1 | alphafold | PREDICTED | 79.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKF2.
Amino-acid sequence (790 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ADAM30?
The strongest Open Targets associations for ADAM30 are Crohn's disease, lymphocyte count, cutaneous melanoma, type 2 diabetes mellitus and diabetes mellitus.
How long is the ADAM30 protein?
The Homo sapiens ADAM30 protein (UniProt Q9UKF2) is 790 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKF2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKF2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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