Cdc42 effector protein 3 (CDC42EP3)
Homo sapiens — UniProt Q9UKI2
Data last refreshed: (UniProt release unknown)
Key facts
Cdc42 effector protein 3 (CDC42EP3) is a protein from Homo sapiens identified by UniProt accession Q9UKI2, 254 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q9UKI2; gene symbol CDC42EP3.
- Organism: Homo sapiens.
- Length: 254 amino acids.
- Top disease associations (Open Targets): body height, cortical surface area measurement and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cdc42 effector protein 3 |
|---|---|
| UniProt accession | Q9UKI2 |
| Gene | CDC42EP3 |
| Organism | Homo sapiens |
| Length | 254 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- body height · score 0.49
- cortical surface area measurement · score 0.44
- mean platelet volume · score 0.44
- platelet count · score 0.44
- body fat distribution · score 0.43
- brain volume measurement · score 0.40
- forced expiratory volume · score 0.39
- cortical thickness · score 0.38
- brain measurement · score 0.38
- waist-hip ratio · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKI2-F1 | alphafold | PREDICTED | 58.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKI2.
Amino-acid sequence (254 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDC42EP3?
The strongest Open Targets associations for CDC42EP3 are body height, cortical surface area measurement, mean platelet volume, platelet count and body fat distribution.
How long is the CDC42EP3 protein?
The Homo sapiens CDC42EP3 protein (UniProt Q9UKI2) is 254 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKI2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKI2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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