Pre-B lymphocyte protein 3 (VPREB3)
Homo sapiens — UniProt Q9UKI3
Data last refreshed: (UniProt release unknown)
Key facts
Pre-B lymphocyte protein 3 (VPREB3) is a protein from Homo sapiens identified by UniProt accession Q9UKI3, 123 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q9UKI3; gene symbol VPREB3.
- Organism: Homo sapiens.
- Length: 123 amino acids.
- Top disease associations (Open Targets): coronary artery disease, lymphocyte percentage of leukocytes and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Pre-B lymphocyte protein 3 |
|---|---|
| UniProt accession | Q9UKI3 |
| Gene | VPREB3 |
| Organism | Homo sapiens |
| Length | 123 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- coronary artery disease · score 0.16
- lymphocyte percentage of leukocytes · score 0.11
- lymphocyte count · score 0.11
- plasma fibronectin deficiency · score 0.07
- isolated asymptomatic elevation of creatine phosphokinase · score 0.06
- Hereditary persistence of alpha-fetoprotein · score 0.04
- congenital enteropathy due to enteropeptidase deficiency · score 0.04
- gastric mucosal hypertrophy · score 0.04
- serum IgG glycosylation measurement · score 0.03
- Congenital deficiency in alpha-fetoprotein · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKI3-F1 | alphafold | PREDICTED | 85.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKI3.
Amino-acid sequence (123 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VPREB3?
The strongest Open Targets associations for VPREB3 are coronary artery disease, lymphocyte percentage of leukocytes, lymphocyte count, plasma fibronectin deficiency and isolated asymptomatic elevation of creatine phosphokinase.
How long is the VPREB3 protein?
The Homo sapiens VPREB3 protein (UniProt Q9UKI3) is 123 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKI3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKI3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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