POU domain, class 2, transcription factor 3 (POU2F3)
Homo sapiens — UniProt Q9UKI9
Data last refreshed: (UniProt release unknown)
Key facts
POU domain, class 2, transcription factor 3 (POU2F3) is a protein from Homo sapiens identified by UniProt accession Q9UKI9, 436 residues long. MolForge cross-references it against 0 known binders and 165 disease associations.
- UniProt accession: Q9UKI9; gene symbol POU2F3.
- Organism: Homo sapiens.
- Length: 436 amino acids.
- Top disease associations (Open Targets): vitamin D measurement, neurodegenerative disease and interleukin 25 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | POU domain, class 2, transcription factor 3 |
|---|---|
| UniProt accession | Q9UKI9 |
| Gene | POU2F3 |
| Organism | Homo sapiens |
| Length | 436 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (165)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.48
- neurodegenerative disease · score 0.40
- interleukin 25 measurement · score 0.30
- small cell lung carcinoma · score 0.22
- mean arterial pressure · score 0.21
- body height · score 0.19
- cutaneous melanoma · score 0.18
- nevus count · score 0.18
- intraocular pressure measurement · score 0.17
- body mass index · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKI9-F1 | alphafold | PREDICTED | 59.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKI9.
Amino-acid sequence (436 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with POU2F3?
The strongest Open Targets associations for POU2F3 are vitamin D measurement, neurodegenerative disease, interleukin 25 measurement, small cell lung carcinoma and mean arterial pressure.
How long is the POU2F3 protein?
The Homo sapiens POU2F3 protein (UniProt Q9UKI9) is 436 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKI9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKI9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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