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Paired immunoglobulin-like type 2 receptor beta (PILRB)

Homo sapiens — UniProt Q9UKJ0

Gene: PILRBHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Paired immunoglobulin-like type 2 receptor beta (PILRB) is a protein from Homo sapiens identified by UniProt accession Q9UKJ0, 227 residues long. MolForge cross-references it against 0 known binders and 122 disease associations.

  • UniProt accession: Q9UKJ0; gene symbol PILRB.
  • Organism: Homo sapiens.
  • Length: 227 amino acids.
  • Top disease associations (Open Targets): heel bone mineral density, platelet count and monocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePaired immunoglobulin-like type 2 receptor beta
UniProt accessionQ9UKJ0
GenePILRB
OrganismHomo sapiens
Length227 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (122)

Diseases linked to this target (Open Targets).

  • heel bone mineral density · score 0.22
  • platelet count · score 0.20
  • monocyte count · score 0.19
  • serum albumin measurement · score 0.19
  • electrocardiography · score 0.17
  • caudate nucleus volume · score 0.15
  • age-related macular degeneration · score 0.09
  • platelet crit · score 0.09
  • atrophic macular degeneration · score 0.09
  • wet macular degeneration · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UKJ0-F1alphafoldPREDICTED80.16—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKJ0.

Amino-acid sequence (227 residues)

MGRPLLLPLL LLLQPPAFLQ PGGSTGSGPS YLYGVTQPKH LSASMGGSVE IPFSFYYPWE LAIVPNVRIS WRRGHFHGQS FYSTRPPSIH KDYVNRLFLN WTEGQESGFL RISNLRKEDQ SVYFCRVELD TRRSGRQQLQ SIKGTKLTIT QAVTTTTTWR PSSTTTIAGL RVTESKGHSE SWHLSLDTAI RVALAVAVLK TVILGLLCLL LLWWRRRKGS RAPSSDF

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PILRB?

The strongest Open Targets associations for PILRB are heel bone mineral density, platelet count, monocyte count, serum albumin measurement and electrocardiography.

How long is the PILRB protein?

The Homo sapiens PILRB protein (UniProt Q9UKJ0) is 227 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UKJ0
GenePILRB
OrganismHomo sapiens
Length227
Binders0
Diseases122
View on UniProt