Paired immunoglobulin-like type 2 receptor alpha (PILRA)
Homo sapiens — UniProt Q9UKJ1
Data last refreshed: (UniProt release unknown)
Key facts
Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a protein from Homo sapiens identified by UniProt accession Q9UKJ1, 303 residues long. MolForge cross-references it against 0 known binders and 128 disease associations.
- UniProt accession: Q9UKJ1; gene symbol PILRA.
- Organism: Homo sapiens.
- Length: 303 amino acids.
- Top disease associations (Open Targets): family history of Alzheimer’s disease, Alzheimer disease and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Paired immunoglobulin-like type 2 receptor alpha |
|---|---|
| UniProt accession | Q9UKJ1 |
| Gene | PILRA |
| Organism | Homo sapiens |
| Length | 303 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (128)
Diseases linked to this target (Open Targets).
- family history of Alzheimer’s disease · score 0.30
- Alzheimer disease · score 0.29
- blood protein measurement · score 0.22
- late-onset Alzheimers disease · score 0.19
- heel bone mineral density · score 0.14
- Red cell distribution width · score 0.14
- serum albumin measurement · score 0.13
- monocyte count · score 0.12
- platelet count · score 0.11
- platelet crit · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKJ1-F1 | alphafold | PREDICTED | 69.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKJ1.
Amino-acid sequence (303 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PILRA?
The strongest Open Targets associations for PILRA are family history of Alzheimer’s disease, Alzheimer disease, blood protein measurement, late-onset Alzheimers disease and heel bone mineral density.
How long is the PILRA protein?
The Homo sapiens PILRA protein (UniProt Q9UKJ1) is 303 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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