NTF2-related export protein 1 (NXT1)
Homo sapiens — UniProt Q9UKK6
Data last refreshed: (UniProt release unknown)
Key facts
NTF2-related export protein 1 (NXT1) is a protein from Homo sapiens identified by UniProt accession Q9UKK6, 140 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q9UKK6; gene symbol NXT1.
- Organism: Homo sapiens.
- Length: 140 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hepatocellular carcinoma and urinary bladder carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NTF2-related export protein 1 |
|---|---|
| UniProt accession | Q9UKK6 |
| Gene | NXT1 |
| Organism | Homo sapiens |
| Length | 140 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- hepatocellular carcinoma · score 0.16
- urinary bladder carcinoma · score 0.15
- benign neoplasm of adrenal gland · score 0.06
- mitochondrial DNA measurement · score 0.03
- cystatin C measurement · score 0.03
- metastatic melanoma · score 0.03
- venous thromboembolism · score 0.02
- metabolite measurement · score 0.02
- infection · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKK6-F1 | alphafold | PREDICTED | 94.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKK6.
Amino-acid sequence (140 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NXT1?
The strongest Open Targets associations for NXT1 are neurodegenerative disease, hepatocellular carcinoma, urinary bladder carcinoma, benign neoplasm of adrenal gland and mitochondrial DNA measurement.
How long is the NXT1 protein?
The Homo sapiens NXT1 protein (UniProt Q9UKK6) is 140 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKK6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKK6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.