ADP-sugar pyrophosphatase (NUDT5)
Homo sapiens — UniProt Q9UKK9
Data last refreshed: (UniProt release unknown)
Key facts
ADP-sugar pyrophosphatase (NUDT5) is a protein from Homo sapiens identified by UniProt accession Q9UKK9, 219 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q9UKK9; gene symbol NUDT5.
- Organism: Homo sapiens.
- Length: 219 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and type 2 diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ADP-sugar pyrophosphatase |
|---|---|
| UniProt accession | Q9UKK9 |
| Gene | NUDT5 |
| Organism | Homo sapiens |
| Length | 219 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- body height · score 0.29
- type 2 diabetes mellitus · score 0.27
- diabetes mellitus · score 0.26
- HbA1c measurement · score 0.23
- forced expiratory volume · score 0.22
- glucose measurement · score 0.22
- electrocardiography · score 0.21
- FEV/FVC ratio · score 0.21
- chronic obstructive pulmonary disease · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKK9-F1 | alphafold | PREDICTED | 92.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKK9.
Amino-acid sequence (219 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NUDT5?
The strongest Open Targets associations for NUDT5 are neurodegenerative disease, body height, type 2 diabetes mellitus, diabetes mellitus and HbA1c measurement.
How long is the NUDT5 protein?
The Homo sapiens NUDT5 protein (UniProt Q9UKK9) is 219 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKK9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKK9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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