Skip to content

PR domain zinc finger protein 4 (PRDM4)

Homo sapiens — UniProt Q9UKN5

Gene: PRDM4Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

PR domain zinc finger protein 4 (PRDM4) is a protein from Homo sapiens identified by UniProt accession Q9UKN5, 801 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

  • UniProt accession: Q9UKN5; gene symbol PRDM4.
  • Organism: Homo sapiens.
  • Length: 801 amino acids.
  • Top disease associations (Open Targets): body fat percentage, body height and body weight.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePR domain zinc finger protein 4
UniProt accessionQ9UKN5
GenePRDM4
OrganismHomo sapiens
Length801 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (43)

Diseases linked to this target (Open Targets).

  • body fat percentage · score 0.42
  • body height · score 0.37
  • body weight · score 0.37
  • balding measurement · score 0.36
  • fat body mass · score 0.34
  • neurodegenerative disease · score 0.31
  • neutrophil percentage of leukocytes · score 0.31
  • hair shape measurement · score 0.29
  • Immature Reticulocyte Fraction Measurement · score 0.28
  • sex hormone-binding globulin measurement · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UKN5-F1alphafoldPREDICTED44.00—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKN5.

Amino-acid sequence (801 residues)

MHHRMNEMNL SPVGMEQLTS SSVSNALPVS GSHLGLAASP THSAIPAPGL PVAIPNLGPS LSSLPSALSL MLPMGIGDRG VMCGLPERNY TLPPPPYPHL ESSYFRTILP GILSYLADRP PPQYIHPNSI NVDGNTALSI TNNPSALDPY QSNGNVGLEP GIVSIDSRSV NTHGAQSLHP SDGHEVALDT AITMENVSRV TSPISTDGMA EELTMDGVAG EHSQIPNGSR SHEPLSVDSV SNNLAADAVG HGGVIPMHGN GLELPVVMET DHIASRVNGM SDSALSDSIH TVAMSTNSVS VALSTSHNLA SLESVSLHEV GLSLEPVAVS SITQEVAMGT GHVDVSSDSL SFVSPSLQME DSNSNKENMA TLFTIWCTLC DRAYPSDCPE HGPVTFVPDT PIESRARLSL PKQLVLRQSI VGAEVGVWTG ETIPVRTCFG PLIGQQSHSM EVAEWTDKAV NHIWKIYHNG VLEFCIITTD ENECNWMMFV RKARNREEQN LVAYPHDGKI FFCTSQDIPP ENELLFYYSR DYAQQIGVPE HPDVHLCNCG KECNSYTEFK AHLTSHIHNH LPTQGHSGSH GPSHSKERKW KCSMCPQAFI SPSKLHVHFM GHMGMKPHKC DFCSKAFSDP SNLRTHLKIH TGQKNYRCTL CDKSFTQKAH LESHMVIHTG EKNLKCDYCD KLFMRRQDLK QHVLIHTQER QIKCPKCDKL FLRTNHLKKH LNSHEGKRDY VCEKCTKAYL TKYHLTRHLK TCKGPTSSSS APEEEEEDDS EEEDLADSVG TEDCRINSAV YSADESLSAH K

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PRDM4?

The strongest Open Targets associations for PRDM4 are body fat percentage, body height, body weight, balding measurement and fat body mass.

How long is the PRDM4 protein?

The Homo sapiens PRDM4 protein (UniProt Q9UKN5) is 801 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

Explore PR domain zinc finger protein 4 with MolForge

Find binders, run structure-based screening, and map this target across diseases and approved drugs with our AI-powered platform.

Browse all targets

Quick facts

UniProtQ9UKN5
GenePRDM4
OrganismHomo sapiens
Length801
Binders0
Diseases43
View on UniProt