Urotensin-2 receptor (UTS2R)
Homo sapiens — UniProt Q9UKP6
Data last refreshed: (UniProt release unknown)
Key facts
Urotensin-2 receptor (UTS2R) is a protein from Homo sapiens identified by UniProt accession Q9UKP6, 389 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.
- UniProt accession: Q9UKP6; gene symbol UTS2R.
- Organism: Homo sapiens.
- Length: 389 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, head and neck squamous cell carcinoma and low grade glioma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Urotensin-2 receptor |
|---|---|
| UniProt accession | Q9UKP6 |
| Gene | UTS2R |
| Organism | Homo sapiens |
| Length | 389 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (71)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.27
- head and neck squamous cell carcinoma · score 0.16
- low grade glioma · score 0.14
- blood protein measurement · score 0.11
- nail-patella syndrome · score 0.06
- persistent truncus arteriosus · score 0.06
- heart failure · score 0.04
- Moyamoya disease · score 0.04
- monocyte percentage of leukocytes · score 0.04
- Hepatic steatosis · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKP6-F1 | alphafold | PREDICTED | 76.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKP6.
Amino-acid sequence (389 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UTS2R?
The strongest Open Targets associations for UTS2R are glioblastoma multiforme, head and neck squamous cell carcinoma, low grade glioma, blood protein measurement and nail-patella syndrome.
How long is the UTS2R protein?
The Homo sapiens UTS2R protein (UniProt Q9UKP6) is 389 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKP6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKP6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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