Kallikrein-9 (KLK9)
Homo sapiens — UniProt Q9UKQ9
Data last refreshed: (UniProt release unknown)
Key facts
Kallikrein-9 (KLK9) is a protein from Homo sapiens identified by UniProt accession Q9UKQ9, 250 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q9UKQ9; gene symbol KLK9.
- Organism: Homo sapiens.
- Length: 250 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, vitamin D measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kallikrein-9 |
|---|---|
| UniProt accession | Q9UKQ9 |
| Gene | KLK9 |
| Organism | Homo sapiens |
| Length | 250 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.39
- vitamin D measurement · score 0.07
- blood protein measurement · score 0.05
- systemic scleroderma · score 0.03
- neoplasm · score 0.03
- cardiac hypertrophy · score 0.02
- ovarian serous adenocarcinoma · score 0.02
- pachyonychia congenita · score 0.01
- cancer · score 0.01
- oral squamous cell carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKQ9-F1 | alphafold | PREDICTED | 91.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKQ9.
Amino-acid sequence (250 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KLK9?
The strongest Open Targets associations for KLK9 are neurodegenerative disease, vitamin D measurement, blood protein measurement, systemic scleroderma and neoplasm.
How long is the KLK9 protein?
The Homo sapiens KLK9 protein (UniProt Q9UKQ9) is 250 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKQ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKQ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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