Kallikrein-13 (KLK13)
Homo sapiens — UniProt Q9UKR3
Data last refreshed: (UniProt release unknown)
Key facts
Kallikrein-13 (KLK13) is a protein from Homo sapiens identified by UniProt accession Q9UKR3, 277 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.
- UniProt accession: Q9UKR3; gene symbol KLK13.
- Organism: Homo sapiens.
- Length: 277 amino acids.
- Top disease associations (Open Targets): head and neck squamous cell carcinoma, glioblastoma multiforme and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kallikrein-13 |
|---|---|
| UniProt accession | Q9UKR3 |
| Gene | KLK13 |
| Organism | Homo sapiens |
| Length | 277 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (82)
Diseases linked to this target (Open Targets).
- head and neck squamous cell carcinoma · score 0.23
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.22
- prostate adenocarcinoma · score 0.21
- cutaneous melanoma · score 0.18
- clear cell renal carcinoma · score 0.18
- blood protein measurement · score 0.16
- gastric adenocarcinoma · score 0.16
- lung adenocarcinoma · score 0.11
- squamous cell lung carcinoma · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKR3-F1 | alphafold | PREDICTED | 86.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKR3.
Amino-acid sequence (277 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KLK13?
The strongest Open Targets associations for KLK13 are head and neck squamous cell carcinoma, glioblastoma multiforme, breast adenocarcinoma, prostate adenocarcinoma and cutaneous melanoma.
How long is the KLK13 protein?
The Homo sapiens KLK13 protein (UniProt Q9UKR3) is 277 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKR3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKR3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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