Ergosterol biosynthetic protein 28 homolog (ERG28)
Homo sapiens — UniProt Q9UKR5
Data last refreshed: (UniProt release unknown)
Key facts
Ergosterol biosynthetic protein 28 homolog (ERG28) is a protein from Homo sapiens identified by UniProt accession Q9UKR5, 140 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q9UKR5; gene symbol ERG28.
- Organism: Homo sapiens.
- Length: 140 amino acids.
- Top disease associations (Open Targets): carpal tunnel syndrome, sitting height measurement and lean body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ergosterol biosynthetic protein 28 homolog |
|---|---|
| UniProt accession | Q9UKR5 |
| Gene | ERG28 |
| Organism | Homo sapiens |
| Length | 140 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- carpal tunnel syndrome · score 0.03
- sitting height measurement · score 0.03
- lean body mass · score 0.02
- cancer · score 0.00
- benign prostatic hyperplasia · score 0.00
- hyperplasia · score 0.00
- neoplasm · score 0.00
- hepatocellular carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKR5-F1 | alphafold | PREDICTED | 93.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKR5.
Amino-acid sequence (140 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ERG28?
The strongest Open Targets associations for ERG28 are carpal tunnel syndrome, sitting height measurement, lean body mass, cancer and benign prostatic hyperplasia.
How long is the ERG28 protein?
The Homo sapiens ERG28 protein (UniProt Q9UKR5) is 140 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKR5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKR5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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