Tetraspanin-16 (TSPAN16)
Homo sapiens — UniProt Q9UKR8
Data last refreshed: (UniProt release unknown)
Key facts
Tetraspanin-16 (TSPAN16) is a protein from Homo sapiens identified by UniProt accession Q9UKR8, 245 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9UKR8; gene symbol TSPAN16.
- Organism: Homo sapiens.
- Length: 245 amino acids.
- Top disease associations (Open Targets): breast carcinoma, free cholesterol measurement and total cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tetraspanin-16 |
|---|---|
| UniProt accession | Q9UKR8 |
| Gene | TSPAN16 |
| Organism | Homo sapiens |
| Length | 245 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- breast carcinoma · score 0.25
- free cholesterol measurement · score 0.11
- total cholesterol measurement · score 0.06
- neutrophil count · score 0.05
- leukocyte count · score 0.03
- myeloid white cell count · score 0.02
- triglyceride measurement · score 0.02
- papillary thyroid carcinoma · score 0.01
- acute lymphoblastic leukemia · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKR8-F1 | alphafold | PREDICTED | 84.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKR8.
Amino-acid sequence (245 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSPAN16?
The strongest Open Targets associations for TSPAN16 are breast carcinoma, free cholesterol measurement, total cholesterol measurement, neutrophil count and leukocyte count.
How long is the TSPAN16 protein?
The Homo sapiens TSPAN16 protein (UniProt Q9UKR8) is 245 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKR8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKR8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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