ETS-related transcription factor Elf-5 (ELF5)
Homo sapiens — UniProt Q9UKW6
Data last refreshed: (UniProt release unknown)
Key facts
ETS-related transcription factor Elf-5 (ELF5) is a protein from Homo sapiens identified by UniProt accession Q9UKW6, 265 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.
- UniProt accession: Q9UKW6; gene symbol ELF5.
- Organism: Homo sapiens.
- Length: 265 amino acids.
- Top disease associations (Open Targets): serum urea measurement, blood protein measurement and blood urea nitrogen measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ETS-related transcription factor Elf-5 |
|---|---|
| UniProt accession | Q9UKW6 |
| Gene | ELF5 |
| Organism | Homo sapiens |
| Length | 265 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (88)
Diseases linked to this target (Open Targets).
- serum urea measurement · score 0.35
- blood protein measurement · score 0.35
- blood urea nitrogen measurement · score 0.33
- neurodegenerative disease · score 0.25
- glycoprotein measurement · score 0.24
- neoplasm · score 0.10
- breast cancer · score 0.10
- COVID-19 · score 0.08
- ovarian carcinoma · score 0.08
- cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKW6-F1 | alphafold | PREDICTED | 70.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKW6.
Amino-acid sequence (265 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ELF5?
The strongest Open Targets associations for ELF5 are serum urea measurement, blood protein measurement, blood urea nitrogen measurement, neurodegenerative disease and glycoprotein measurement.
How long is the ELF5 protein?
The Homo sapiens ELF5 protein (UniProt Q9UKW6) is 265 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKW6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKW6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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