Integrin alpha-11 (ITGA11)
Homo sapiens — UniProt Q9UKX5
Data last refreshed: (UniProt release unknown)
Key facts
Integrin alpha-11 (ITGA11) is a protein from Homo sapiens identified by UniProt accession Q9UKX5, 1188 residues long. MolForge cross-references it against 0 known binders and 245 disease associations.
- UniProt accession: Q9UKX5; gene symbol ITGA11.
- Organism: Homo sapiens.
- Length: 1188 amino acids.
- Top disease associations (Open Targets): uterine fibroid, cortical surface area measurement and BMI-adjusted waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Integrin alpha-11 |
|---|---|
| UniProt accession | Q9UKX5 |
| Gene | ITGA11 |
| Organism | Homo sapiens |
| Length | 1188 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (245)
Diseases linked to this target (Open Targets).
- uterine fibroid · score 0.39
- cortical surface area measurement · score 0.38
- BMI-adjusted waist-hip ratio · score 0.38
- protein measurement · score 0.36
- BMI-adjusted hip circumference · score 0.36
- systolic blood pressure · score 0.31
- facial morphology measurement · score 0.31
- Dupuytren Contracture · score 0.30
- brain measurement · score 0.29
- waist-hip ratio · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKX5-F1 | alphafold | PREDICTED | 85.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKX5.
Amino-acid sequence (1188 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ITGA11?
The strongest Open Targets associations for ITGA11 are uterine fibroid, cortical surface area measurement, BMI-adjusted waist-hip ratio, protein measurement and BMI-adjusted hip circumference.
How long is the ITGA11 protein?
The Homo sapiens ITGA11 protein (UniProt Q9UKX5) is 1188 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKX5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKX5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.