Nuclear pore complex protein Nup50 (NUP50)
Homo sapiens — UniProt Q9UKX7
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear pore complex protein Nup50 (NUP50) is a protein from Homo sapiens identified by UniProt accession Q9UKX7, 468 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q9UKX7; gene symbol NUP50.
- Organism: Homo sapiens.
- Length: 468 amino acids.
- Top disease associations (Open Targets): HIV infection, influenza and viral disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear pore complex protein Nup50 |
|---|---|
| UniProt accession | Q9UKX7 |
| Gene | NUP50 |
| Organism | Homo sapiens |
| Length | 468 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.54
- influenza · score 0.54
- viral disease · score 0.53
- COVID-19 · score 0.37
- Histiocytosis · score 0.37
- mean corpuscular volume · score 0.31
- clear cell renal carcinoma · score 0.28
- mean corpuscular hemoglobin concentration · score 0.27
- endometrial cancer · score 0.23
- mean corpuscular hemoglobin · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKX7-F1 | alphafold | PREDICTED | 64.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKX7.
Amino-acid sequence (468 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NUP50?
The strongest Open Targets associations for NUP50 are HIV infection, influenza, viral disease, COVID-19 and Histiocytosis.
How long is the NUP50 protein?
The Homo sapiens NUP50 protein (UniProt Q9UKX7) is 468 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKX7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKX7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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