Prion-like protein doppel (PRND)
Homo sapiens — UniProt Q9UKY0
Data last refreshed: (UniProt release unknown)
Key facts
Prion-like protein doppel (PRND) is a protein from Homo sapiens identified by UniProt accession Q9UKY0, 176 residues long. MolForge cross-references it against 0 known binders and 167 disease associations.
- UniProt accession: Q9UKY0; gene symbol PRND.
- Organism: Homo sapiens.
- Length: 176 amino acids.
- Top disease associations (Open Targets): glomerular filtration rate, hair color and azoospermia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Prion-like protein doppel |
|---|---|
| UniProt accession | Q9UKY0 |
| Gene | PRND |
| Organism | Homo sapiens |
| Length | 176 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (167)
Diseases linked to this target (Open Targets).
- glomerular filtration rate · score 0.22
- hair color · score 0.20
- azoospermia · score 0.12
- visual perception measurement · score 0.11
- male infertility with teratozoospermia due to single gene mutation · score 0.10
- spermatogenic failure 20 · score 0.10
- spermatogenic failure 5 · score 0.10
- spermatogenic failure 53 · score 0.10
- spermatogenic failure 31 · score 0.10
- spermatogenic failure 26 · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKY0-F1 | alphafold | PREDICTED | 76.96 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKY0.
Amino-acid sequence (176 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRND?
The strongest Open Targets associations for PRND are glomerular filtration rate, hair color, azoospermia, visual perception measurement and male infertility with teratozoospermia due to single gene mutation.
How long is the PRND protein?
The Homo sapiens PRND protein (UniProt Q9UKY0) is 176 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKY0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKY0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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