Procollagen C-endopeptidase enhancer 2 (PCOLCE2)
Homo sapiens — UniProt Q9UKZ9
Data last refreshed: (UniProt release unknown)
Key facts
Procollagen C-endopeptidase enhancer 2 (PCOLCE2) is a protein from Homo sapiens identified by UniProt accession Q9UKZ9, 415 residues long. MolForge cross-references it against 0 known binders and 106 disease associations.
- UniProt accession: Q9UKZ9; gene symbol PCOLCE2.
- Organism: Homo sapiens.
- Length: 415 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Procollagen C-endopeptidase enhancer 2 |
|---|---|
| UniProt accession | Q9UKZ9 |
| Gene | PCOLCE2 |
| Organism | Homo sapiens |
| Length | 415 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (106)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- body height · score 0.37
- blood protein measurement · score 0.37
- pulse pressure measurement · score 0.35
- appendicular lean mass · score 0.35
- total cholesterol measurement · score 0.32
- endothelin-converting enzyme 1 measurement · score 0.28
- heel bone mineral density · score 0.26
- fatty acid measurement · score 0.26
- arachidonic acid measurement · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UKZ9-F1 | alphafold | PREDICTED | 81.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UKZ9.
Amino-acid sequence (415 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCOLCE2?
The strongest Open Targets associations for PCOLCE2 are neurodegenerative disease, body height, blood protein measurement, pulse pressure measurement and appendicular lean mass.
How long is the PCOLCE2 protein?
The Homo sapiens PCOLCE2 protein (UniProt Q9UKZ9) is 415 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UKZ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UKZ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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