Zinc finger protein 214 (ZNF214)
Homo sapiens — UniProt Q9UL59
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 214 (ZNF214) is a protein from Homo sapiens identified by UniProt accession Q9UL59, 606 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q9UL59; gene symbol ZNF214.
- Organism: Homo sapiens.
- Length: 606 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, breast carcinoma and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 214 |
|---|---|
| UniProt accession | Q9UL59 |
| Gene | ZNF214 |
| Organism | Homo sapiens |
| Length | 606 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- breast carcinoma · score 0.04
- blood protein measurement · score 0.02
- Beckwith-Wiedemann syndrome · score 0.02
- Intellectual disability · score 0.01
- Obesity · score 0.01
- cryptorchidism · score 0.00
- cancer · score 0.00
- neoplasm · score 0.00
- Sjogren syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UL59-F1 | alphafold | PREDICTED | 62.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UL59.
Amino-acid sequence (606 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF214?
The strongest Open Targets associations for ZNF214 are neurodegenerative disease, breast carcinoma, blood protein measurement, Beckwith-Wiedemann syndrome and Intellectual disability.
How long is the ZNF214 protein?
The Homo sapiens ZNF214 protein (UniProt Q9UL59) is 606 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UL59 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UL59 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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